The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Society Featured Lecture

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day3)

Workshops

Lunchtime Seminars (Day1, Day2, Day3)

Oral Sessions

Day 2, May 20（Thu.）　11:20-11:40　Room B (Zoom)

2B-O7-1120　　PDF

Liquid Chromatography – Tandem Mass Spectrometry-based Characterization of Long, Modified Ribonucleic Acids

(RIKEN CSRS)
oHiroshi Nakayama

An analytical platform consisting of nano-flow liquid chromatography - tandem mass spectrometry and informatics system has been developed for characterizing post-transcriptionally modified cellular RNAs in femtomole amounts. The platform is updated to enable the characterization of chemical structures of therapeutic nucleic acids. In this talk, applications of the platform to the analysis of long, modified RNAs including 5'-capped ones will be presented.