Abstract

Table of contents

Plenary Lectures: Award Lectures
Oral Sessions Day1, Day2, Day3: Poster Presentations Day1, Day2, Day3
Workshop: Luncheon Seminars Day1, Day2, Day3
Timetable

Poster Presentations

Day 2, May 18（Thu.）　　Room P (Multi-purpose Hall)

2P-47　　PDF

Quantitation method for glycoforms of monoclonal antibodies using a novel internal standard

(¹Yokohama City Univ., ²Yokohama City Univ., ³YBRS, ⁴Kihara Memorial Yokohama Foundation)
^oMinami Maehara¹, Yuki Ohta², Daisuke Takakura², Hiroki Matsuno³, Hideyuki Goto³, Daisuke Arinobu⁴, Nana Kawasaki^1,2

We developed a quanititation method for glycoforms of monoclonal antibodies using a novel internal standard prepared from a mAb by treating with endoglycosidases. This method provides a linearity with r=0.994 for major glycoforms in the range of 10-500 fmol and is expected to be used for quality control of mAb products.