2C-O1-0950（2P-11） PDF
Metaproteome analysis of disease model mice
We developed shotgun proteomic approaches to acquire metaproteome profiles of gastrointestinal systems in human disease model mice. For stomach, intestine, colon as well as feces, we successfully identify thousands of mouse proteins, enterobacterial proteins and proteins from mouse feed. This approach is useful to examine the interaction between intestinal bacteria and the host at the proteome level under the various disease conditions.