Abstract

Poster Presentations

Day 1, May 17(Wed.)  Room P (Multi-purpose Hall)

Metabolomic Workflow Utilising Rapid Microbore Metabolic Profiling (RAMMP) In Conjunction with a Novel Scanning Quadrupole DIA Method

(1Waters, 2Nihon Waters)
Lee Gethings1, Chris Hughes1, Richardson Keith1, Wildgoose Jason1, Vissers Johannes1, James Langridge1, oThanai Paxton2

Introduction

Previous studies utilizing rapid microbore metabolic profiling (RAMMP) have shown comparable group discrimination and improved selectivity over conventional UPLC chromatography. Here we demonstrate improvements of the workflow by coupling RAMMP with a novel DIA method (SONAR) to provide qualitative and quantitative information for metabolomic based applications.

Novel Aspect

Implementation of RAMMP with a novel DIA (SONAR) workflow results in higher and more confident numbers of metabolite identifications at increased sample throughput.