1P-30 PDF
Online LC/MS analysis on the phosphate buffer using the desalination system
Because the detection is possible at the low wavelength, phosphate buffer is frequently used for a mobile phase for HPLC. However, it is difficult to use it for the online LC/MS analysis because the phosphate buffer is nonvolatile. Therefore we developed a method of the online LC/MS analysis under the condition of phosphate buffer by converting phosphate ions into volatile ions, using ion-exchange resin.