1B-O1-1625 PDF
Development of Certified Reference Materials for Analysis of Steroid Hormones in Human Serum by Using Isotope Dilution Mass Spectrometry
Recently, the reliability of clinical test value is important issue. In order to construct a measurement traceability system to SI, it is necessary to develop Certified Reference Material (CRM). We developed CRM (NMIJ CRM 6401-b) for analysis of cortisol in human serum sample by using Isotope Dilution Mass Spectrometry (IDMS). Also, we participated in international key comparison such as CCQM K63. The results were registered in the Key Comparison Database (KCDB) as Calibration and Measurement Capabilities (CMC). In addition, the NMIJ CRM 6401-b was registered in Joint Committee on Traceability in Laboratory Medicine (JCTLM) list 1. This CRM is intended primarily for use in calibration of analytical instrument and evaluating the accuracy and validation of analytical procedures or instruments for the determination of cortisol in human serum by instrumental analysis.