演題概要

オーラルセッション

第1日 6月17日(水) 16:05~16:25 C会場(101)

マダラサソリの毒液に含まれる抗菌性ペプチドのde novoシーケンス解析

(京大院農)
o北中淳史宮下正弘中川好秋宮川恒

Scorpion venom contains antimicrobial peptides besides neurotoxins. In this study, we searched for antimicrobial peptides from the venom of the scorpion Isometrus maculatus based on the structural feature. Primary structures of the peptides were determined by de novo sequencing using both low-energy and high-energy collision-induced dissociation, with a support of the genetic information. As a result of sequence similarity search, the peptides obtained in this study are likely to have antimicrobial property.