The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Workshops

Luncheon Seminars (Day1, Day2, Day3)

Poster Presentations

Day 3, May 13（Wed.）　　Poster (1008/09)

3P-36　　PDF

Approach to simplification of measurement method in plasma protein binding screening

(Ono Pharm.)
oYoshimi Kojima, Jyunya Kato, Ryuichi Harada, Yoshiyuki Yamaura

Plasma protein binding(PPB) is an important determinant in the pharmacokinetics,　pharmacodynamics, and safety of drugs. At the early stages of drug development, we need to evaluate many compounds more quickly for PPB. Therefore, we tried to simplify the measurement with the aim of speed up the protein binding screening.