Poster Presentations
- Day 3, May 13（Wed.） Poster (1008/09)
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3P-26 PDF
Protein Structure Analysis by Peptide Mapping with On-line Disulfide bond Reduction
Disulfide bond deeply involves into a conformation of proteins. And therefore, disulfide scrambling analysis is a part of critical quality attributes (CQAs) of the therapeutic monoclonal antibodies. We will show the new approach to determine the site of disulfide scrambling by post-column reduction