The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Workshops

Luncheon Seminars (Day1, Day2, Day3)

Poster Presentations

Day 3, May 13（Wed.）　　Poster (1008/09)

3P-24　　PDF

Molecular Mass Estimation Method using Spectral Change with the Desolvation Temperature in an Electrospray Ionization

(1MS Solutions, 2Hamamatsu Univ. Sch. Med., 3Preppers)
oYutaka Takahashi1,2,3

Electrospray ionization　(ESI), the most general ionization method in LC/MS, is a representative example of soft ionization, and usually does not generate fragment ions. However, in some compounds which have a hydroxyl group, [M+H]+, [M+Na]+, [M+NH4]+, etc. are not generated by positive ions, and dehydration from [M+H]+ and [M+H-H2O]+ are mainly observed. If such ions are observed in the measurement of an unknown sample, it will cause inconvenience when acquiring mass information of the analyte. In this study, in the ESI used for LC/MS, the dehydration ions [M+H-H2O]+ from [M+H]+ are mainly observed at normal desolvation temperatures. This paper reports a method for obtaining mass information of an analyte correctly from changes in mass spectral patterns by lowering the desolvation temperature. The performance was demonstrated using cholesterol, eudesmol and hinesol.