Oral Sessions
- Day 3, May 13（Wed.） 14:30-14:50 Room A (Main Hall)
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3A-O13-1430 PDF
Development of basic technologies for non-targeted metabolomics
In recent years, more than 1000 metabolite peaks have been detected in various biological samples because of the rapid development of high-resolution mass spectrometry and data mining techniques. However, only approximately 10% of metabolites can be identified in the detected peaks. Therefore, it is necessary to develop a methodology that enables structure estimation of metabolite peaks obtained by non-target metabolomic analysis. Furthermore, it is important to proceed with structure estimation (identification) of metabolites that can be candidates for new bioactive metabolites or biomarkers among unknown metabolites. In this study, we introduce strategies for efficient metabolite identification from non-targeted metabolome data obtained by liquid chromatography high-resolution mass spectrometry.