The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan

Abstract

Poster Presentations

Day 2, May 12(Tue.)  Poster (1008/09)

Search for iPSC-derived neural differentiation markers using LC/MS/MS

(Yokohama City Univ.)
oTakaya Urasawa, Takumi Koizumi, Kazumasa Kimura, Yuki Ohta, Nana Kawasaki

Induced pluripotent stem cells (iPSCs)-derived neural differentiated cells are expected to be applied to regenerative medicine. Effective quality control methods, especially biomarkers that can be used for the early stage of neural differentiation, are needed to achieve the regenerative medicine. In this study, we conducted LC/MS/MS with a data-independent acquisition (DIA) approach for comparative proteomics of iPSCs and neural stem cells (NSCs) and found some marker candidates for the early stage of neural differentiation.