The Mass Spectrometry society of Japan - The 68th Annual Conference on Mass Spectrometry, Japan
Japanese

Abstract

Table of contents

Timetable

Plenary Lectures

Oral Sessions (Day1, Day2, Day3)

Poster Presentations (Day1, Day2, Day3)

Workshops

Luncheon Seminars (Day1, Day2, Day3)

Oral Sessions

Day 2, May 12（Tue.）　9:05-9:25　Room A (Main Hall)

2A-O4-0905　　PDF

Development of high throughput LC-MS imaging system using thermal film-based laser microdissection and parallel LC

(1Shimadzu, 2Nagoya Univ.)
oYusuke Koga1, Youngsoon Hong1, Ryuta Matsumoto1, Hiromi Suzuki2, Kenji Ono2, Hiroki Maeda1, Kiyoshi Ogawa1, Makoto Sawada2

Mass spectrometry imaging(MSI) is a powerful tool for visualize spatial distribution of molecules. Although MALDI-MSI is widely used in pharmacokinetics, metabolite analysis, biomarker search, it has several disadvantages in high sensitivity analysis or quantitative analysis. On the other hand, LC-MS is a great tool for high sensitivity quantitative analysis of molecules. However, LC-MS imaging is difficult in terms of sample preparation and throughput. In this study, we have developed high throughput LC-MS imaging system using thermal film-based laser microdissection and parallel LC.