演題概要

ポスター発表

第２日　５月１５日（木）　　会場（月光）

2P-14　　PDF

Mass++: 同定機能と翻訳後修飾文献DBとの連携

(¹島津・ ²エーザイ)
^o田中聡¹・ 吉沢明康¹・ 田畑剛²・ 草野麻衣子¹・ 青島健²・ 宇都宮眞一¹・ 梶原茂樹¹・ 小田吉哉²・ 田中耕一¹

Proteome database search engines such as Mascot and X! Tandem are commonly used for protein identification. Results from such engines contain variable modification information, but evaluating whether the modification is a known or unknown one is not always trivial. We developed a known PTM literature database based on the XML version of Swiss-Prot and have implemented a function that retrieves literature information using the protein name, PTM category, and the PTM position in the protein as the queries. We integrated the protein identification results with the PTM literature information from the database, which are then displayed on Mass++, our developing visualization and analysis tool for mass spectrometry.