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Symposia
Room A (The Life Hall)
S1 [The first microdosing level crossover clinical study in Japan]
(Day 1 May 17, Wed., 16:30-18:30, Room A)
(16:30-18:30) Organizer: Zenzaburo Tozuka (JCL Bioassay Co.)
1A-S1-1630 Clinical Pharmacology Study using the technique of Microdose Clinical Trial
( 1Kitasato University East Hospital, 2Kitasato University, 3JCL bioassay corporation, 4JCL bioassay corporation, 5University of Tokyo)
oYuji Kumagai1, Akira Yamazaki2, Naoe Yamane3, Zenzaburou Tozuka4, Yuichi Sugiyama5
1A-S1-1700 Determination of Drug Concentration in Human Plasma using LC/ESI-MS/MS at a Microdose
( 1JCL Bioassay Corporation, 2JCL Bioassay Corporation, 3Graduate School of Pharmaceutical Sciences The University of Tokyo, 4Kitazato University Graduate School of Medicine, 5Clinical Investigation Center, Kitazato University East Hospital)
oNaoe Yamane1, Zenzaburou Tozuka2, Yuichi Sugiyama3, Akira Yamazaki4, Yuji Kumagai5
1A-S1-1730 Is the prediction of pharmacokinetics at therapeutic dose from that at microdose possible ?
( The University of Tokyo)
oYuichi Sugiyama
1A-S1-1800 Considerations on the safety of microdose clinical trisls
( InCROM)
oHiroshi Mayahara
Room A (The Life Hall)
S2 [Pharmacokinetics -for making it more efficient and sensitive-]
(Day 2 May 18, Thu., 9:00-11:00, Room A)
(9:00-11:00) Organizers: Shingo Horimoto (Tanabe Seiyaku Co., Ltd.) , Yoshihiko Takinami (Shionogi & Co., Ltd.)
2A-S2-0900 A perspective on structural elucidation of metabolites in drug discovery and development
( Astellas Inc.)
oKazuyoshi Nozaki
2A-S2-0930 Advancement of High Sensitivity Measurement for Drug in Human Plasma By LC/MS/MS Systems
( JCL Bioassay)
oAki Koyama, Hisami Murai
2A-S2-1000 Automated Sensitive Method Using LC/APCI-MS/MS with PROSPEKT-2TM On-Line Solid-Phase Extraction in pharmacokinetic studies.
( Drug Metabolism and Pharmacokinetics Research Laboratories, Sankyo Co., Ltd.)
oKiyoshi Kawabata, Yoko Urasaki
2A-S2-1030 Sensitivity Enhancement in LC-MS/MS using 1-alkylamine additives
( Takeda Pharmaceutica Company Ltd.)
oKoichiro Teshima
Room A (The Life Hall)
S3 [Proteomics -Present and Future-]
(Day 2 May 18, Thu., 15:00-17:00, Room A)
(15:00-17:00) Organizers: Toshifumi Takao (Osaka Univ.) , Natsume Tohru (AIST)
2A-S3-1500 Evolutional proteomics mass spectrometry
( Institute for Advanced Biosciences, Keio University)
oYasushi Ishihama
2A-S3-1530 Proteomic analysis towards biomarker discovery
( Inst. Protein Res. Osaka Univ.)
oToshifumi Takao
2A-S3-1600 Trends and Challenges in Protein Identification
( Matrix Science)
oJohn Cottrell
2A-S3-1630 Chemical Biology Project in Japan
( AIST)
oTohru Natsume
Room B (The Science Hall)
S4 [Instrumentation for the 21st century]
(Day 2 May 18, Thu., 15:00-17:00, Room B)
(15:00-17:00) Organizer: Morio Ishihara (Osaka Univ.)
2B-S4-1500 Developments and Applications of a Miniaturized,Highly Sensitive Magnetic Sector Mass Spectrometer,"Elfie"
( 1Dune,Inc, 2Dune,Inc, 3Dune,Inc)
oHiroshi Tomiyama1, Noriko Mori2, Masahiko Sakai3
2B-S4-1520 High Mass MALDI-MS/MS Analysis using Rectangular Waveform Driven 3D-QIT
( 1Shimadzu Corp., 2SRL)
Sadanori Sekiya1, Shinichi Iwamoto1, Li Ding2, oKoichi Tanaka1
2B-S4-1540 Development of a high-performance time-of-flight mass spectrometer utilizing a spiral ion trajectory
( JEOL)
oTakaya Satoh
2B-S4-1600 Simulation of ion motion and spectra in FT-ICR mass spectrometry
( Hiroshima City Univ.)
oMakoto Fujiwara
2B-S4-1620 Development of miniature double-focusing mass spectrograph for lunar exploration
( Osaka Univ.)
oMorio Ishihara
Room A (The Life Hall)
S5 [Recent innovations in the MS backbone: from ionization to detection]
(Day 3 May 19, Fri., 15:00-17:00, Room A)
(15:00-17:00) Organizer: Yoshinao Wada (Osaka MCHRI)
3A-S5-1500 Breakthrough of the ionization methods forthe next generation
( Univ. of Yamanashi)
oKenzo Hiraoka
3A-S5-1530 Relation between dissociation induced by electron transfer and charge number of the primary ion
( Osaka Pref.Univ.)
oShigeo Hayakawa
3A-S5-1600 Potential for new mass spectroscopy with superconducting detectors
( AIST)
oMasataka Ohkubo
3A-S5-1630 Tandem Mass Spectrometry by High Energy CID using Multi-turn Tandem TOF Mass Spectrometer
( Osaka Univ.)
oMichisato Toyoda
Room B (The Science Hall)
S6 [Imaging mass spectrometry]
(Day 3 May 19, Fri., 15:00-17:00, Room B)
(15:00-17:00) Organizer: Yasuhide Naito (GPI)
3B-S6-1500 Surface Characterization of Industrial Materials by Using TOF-SIMS Imaging
( Toyota CRDL)
oAtsushi Murase
3B-S6-1530 TOF-SIMS Imaging Technology for Biodevices
( Shimane Univ.)
oSatoka Aoyagi
3B-S6-1600 Optimization of Sample Preparation for Mass Microscopy
( 1NINS, 2NIPS, 3OIIB, 4MITILS)
omitsutoshi setou1,2,3,4
3B-S6-1630 Design Concept of Mass Spectrometric Camera
( 1GPI, 2Osaka Univ., 3SUNBOR, 4CREST, JST)
oYasuhide Naito1,4, Kunio Awazu2,4, Michisato Toyoda2,4, Ken-ichi Fujii2,4, Katsuyoshi Masuda3,4
Room C
S7 [Isotopic medical examination and food environment]
(Day 3 May 19, Fri., 15:00-17:00, Room C)
(15:00-17:00) Organizers: Jun-ichi Matsuda (Osaka Univ) , Takafumi Hirata (TITech)
3C-S7-1500 Stable isotopes as tools for ecological and paleoenvironmental studies
( 1IFREE, 2EPS, 3FRCGC)
oNanako O. Ogawa1, Hidetaka Nomaki1, Yuichiro Kashiyama2, Yoshito Chikaraishi1, Eitaro Wada3, Naohiko Ohkouchi1, Hiroshi Kitazato1
3C-S7-1520 Stable isotope analysis as a cluew of human feeding ecology
( GSES HOKKAIDO UNIV)
oMasao Minagawa
3C-S7-1540 Application of Strontium Isotope Ratio Analysis to the Determination of the Geographic Origin of Agricultural Products
( 1Natl. Inst. Agro-Environ. Sci., 2Eisai Seikaken Co., Ltd.)
oAkira Kawasaki1, Hisao Oda1,2
3C-S7-1600 Carbon isotopic variation of human breath and metabolism inside the bod
( 1Osaka University, 2Tsukuba University)
oJun-ichi Matsuda1, Teruyuki Maruoka2
3C-S7-1620 Synthesis of 13C-Labelled Compounds and 13C-Breath Test
( M.P.C.)
oMasahiro Kajiwara
3C-S7-1640 Isotopic Fractionations of Fe and Ca through Metabolic Process
( 1TITech, 2Juntendo Univ.)
oTakafumi Hirata1, Atsuko Shinohara2, Momoko Chiba2, Tsuyoshi Ohno1, Akinobu Suga1, Mina Tanoshima1
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