Poster Presentations
Day 2, June 11（Thu.） Room P (5F 501+502)
- 2P-43
Comprehensive PFAS Monitoring from Ultra Short to Long Chain Compounds by SFC–QTOF
(Agilent)
oKyohko Yasuda, Akio Hayashi, Hirokazu Sawada
Ultra‑short PFAS (C1–C3), including TFMS, PFEtS, PFPrS, TFA, and PFPrA, are increasingly used as replacements for long‑chain PFAS and have emerged as important environmental contaminants. Their extremely high polarity makes them difficult to retain in conventional LC–MS workflows. In this study, we introduce an SFC‑QTOF method capable of separating and detecting PFAS across a broad carbon‑chain range (C1–C12). By leveraging the high diffusivity and unique selectivity of supercritical CO₂, the method achieved stable retention and high‑resolution separation using a 2‑ethylpridine column. This approach provides a unified and high‑throughput platform for the analysis of diverse PFAS classes in complex matrices.