Proposed Sessions
Day 2, June 11（Thu.） 9:15-9:45 Room D (5F 511+512)
- 2D-P1-0915
Mass Spectrometry Imaging – New technology for spatial omics –
(The Univ. Osaka)
oShuichi Shimma
Mass Spectrometry Imaging (MSI) has emerged as a cornerstone of spatial omics, uniquely integrating label-free molecular profiling with precise histological localization. Once limited to simple distribution mapping, recent breakthroughs in instrumentation and preprocessing have propelled MSI toward single-cell and subcellular resolutions, fundamentally redefining the landscape of life science research. This presentation provides an overview of the latest technological trajectories in MSI, emphasizing advancements in optical systems and ion sources. A central focus is the rise of "multimodal integration"—a transformative shift where MSI is combined with diverse microscopy and other omics modalities. Furthermore, I highlight the role of machine learning-driven MSI informatics in decoding vast datasets to achieve "spatial molecular profiling" that transcends mere visualization.Drawing from cutting-edge applications in medicine, botany, and food science (such as fermentation processes), this talk showcases how MSI serves as a powerful engine for "discovering the unknown" within complex contexts. By synthesizing these innovations, we aim to discuss the future of next-generation MSI as an indispensable analytical frontier.