Symposium Sessions
Day 1, June 10（Wed.） 15:30-16:00 Room B (4F 411+412)
- 1B-S2-1530
Systems Biology Research Driven by High-Throughput Proteomics (Niigatra University 1)
(Niigata Univ.)
oMasaki Matsumoto
Recent advances in mass spectrometry technologies and computational data analysis have enabled truly high-throughput and comprehensive proteomic measurements, fundamentally reshaping our understanding of how proteomes can be studied. Rather than being viewed as static inventories of protein abundance, proteomes are increasingly recognized as dynamic and context-dependent systems that continuously respond to cellular states, environmental cues, and temporal changes.
In this talk, I will present an overview of emerging frontiers in proteome research driven by high-throughput proteomics from a systems biology perspective. The integration of multiple layers of information—including protein abundance, subcellular localization, molecular interactions, complex organization, and metabolic context—provides new conceptual frameworks for understanding cellular functions as coordinated biological systems.
I will also discuss how proteome plasticity and large-scale molecular reorganization relate to evolution and adaptation, illustrating the growing potential of proteomics to address fundamental questions in biology. This talk will highlight the current landscape and future directions of systems biology research empowered by modern proteomics.