演題概要

ポスター発表

第3日　5月17日（水）　　P会場（ホワイエ，会議室1004-1007）

3P-40　　PDF

LC/MS用分離技術「真空示差イオンモビリティ分析装置」の開発

(¹島津・ ²島津(欧州)・ ³ジュネーブ大)
^o洪暎淳¹・ 石井俊匡¹・ 矢嶋敦¹・ 前田裕樹¹・ 小河潔¹・ 古橋治¹・ Knight, Patrick²・ Entwistle, Andrew²・ Girard, Maria Fernanda Cifuentes³・ Hopfgartner, Gerard³

Differential mobility spectrometry (DMS) separates ions based on the nonlinear change in their mobility between high to low electric fields, which are elicited in a field asymmetric waveform applied to electrodes. This nonlinear change in mobility has less dependence on a molecular weight, and thus DMS can be useful for separation of structural isomers and isobars. The mobility coefficient in DMS can be expanded by nonlinear terms of E/N (E: Electric field strength, N: Gas density). Therefore, higher E/N gives greater change in mobility and result in higher resolution. We have developed vacuum DMS, which reduces gas density N and gives higher E/N than conventional atmospheric DMS. Here we introduce the principle of vacuum DMS and show the examples of analyses using LC-vacuum DMS-MS.