日本質量分析学会 第71回質量分析総合討論会

演題概要

ポスター発表

第2日 5月16日(火)  P会場(ホワイエ,会議室1004-1007)

データ非依存的取得質量分析法を用いた細胞内O-GlcNAc修飾タンパク質の定量解析

(横市大院生命医)
o保科隼佑浦澤貴哉西村梨香高倉大輔川崎ナナ

An O-GlcNAcylated peptide spectral library was created by data-dependent acquisition mass spectrometry of O-GlcNAcylated peptides from human induced pluripotent stem cells (hiPSC). Using the library, we performed data-independent mass spectrometry of iPSC and iPSC-derived neural stem cells and neuron. O-GlcNAcylation of host cell factor 1 was found to be altered during neuronal differentiation.