日本質量分析学会 第71回質量分析総合討論会

演題概要

ポスター発表

第1日 5月15日(月)  P会場(ホワイエ,会議室1004-1007)

イオンモビリティーを用いたLC/MSおよびレーザー脱離イオン化質量分析イメージングによる毛髪中の代謝物の分析

(1富山県立大2富山県立大院工3金沢大国基)
o高田莉子1山川舞2島﨑泰地2唐島成宙3大坂一生1,2

Human blood metabolites are accumulated into hair. The metabolites in the hair reflects the time-averaged composition in the blood circulation. Therefore, the analysis of the metabolites in the hair allows to assess human health. It has become increasingly important to establish a rapid and comprehensive analytical method of its metabolites for the assessment. In this study, we developed the LC/MS coupled with ion mobility for the analytical method for targeted quantitative and non-targeted qualitative analysis simultaneously. In addition, laser desorption/ionization mass spectrometry imaging was also applied for the metabolite profiling.