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北アフリカ生息種サソリButhacus leptochelys毒液に含まれる直鎖状ペプチドのde novo sequencing解析
Scorpions utilize venom to capture prey and protect themselves from predators by showing neurotoxicity against insects and mammals. The scorpion venom contains various components, in which peptides are main components responsible for the activities of the venom. Most of these peptides contain multiple disulfide bonds, but linear peptides without disulfide bonds are also present in the venom, which often exhibit antimicrobial activity. In this study, we searched for a linear peptide from the venom of the North African scorpion Buthacus leptochelys and determined its structure using de novo sequencing analysis.