ポスター発表
- 第3日 5月17日（木） ポスター会場
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3P-19 PDF
LC/QTOFとGC/MSを用いた医薬品容器・包装からの抽出物/浸出物の解析
Drug substances and products can be contaminated by chemical compounds from primary and secondary packaging materials. Compounds which can be extracted directly from the container closure systems are called “extractables” while compounds, which are found within the formulation are called “leachables” which are often a subset of extractables. As the multiple and often complementary analytical techniques, LC/MS and GC/MS are used for Extractables & Leachables (E&L) screening. LC/MS and GC/MS technique enables the rapid and efficient identification of E&L.