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ポスター発表

第2日　5月16日（水）　　ポスター会場

2P-19　　PDF

DMT-MMを用いたペプチドN末端アミノ基の選択的修飾法

(京大院農)
^o十一浩典・ 北中淳史・ 二橋陽一郎・ 宮下正弘・ 宮川恒

Modification of the peptide N-terminus with a charged tag is known to affect MS/MS fragmentation, which can facilitate the MS-based de novo sequencing. However, N-terminal specific introduction of the tag molecule often requires laborious and time-consuming preparation of reagents. In this study, we examined a facile method to introduce a charged tag specifically to the peptide N-terminus by using a condensation reagent, DMT-MM.