受賞講演
- 第2日 5月16日（水） 10:45～11:05 A会場（オービットホール）
-
2A-AW-1045 PDF
質量分析を用いた一次代謝の定量分析に関する研究
Mass spectrometry-based methods for quantitative evaluation of the central metabolism were developed by taking an advantage of mass spectrometry including targeted proteome analysis, absolute quantification of intracellular metabolic intermediates, and 13C-based metabolic flux analysis. These methodologies were applied for analyses of microbial cell factories and cancer cells to investigate metabolic bottlenecks in the metabolic networks and metabolic rewiring mechanisms to maintain a metabolic homeostasis.