Abstract

Poster Presentations

Day 3: Friday, May 20  Poster Room(Gekko)

Study on Measurement of Blood Thiosulfate using LC-MS/MS

(1Hokkaido Univ., 2Hokkaido Univ.)
oShigeki Jin1, Kotaro Matoba2, Hideki Hyodoh2, Sanae Haga1, Michitaka Ozaki1

Thiosulfate measurement is crucial to diagnosis of hydrogen sulfide (H2S) poisoning in forensic toxicology. Although GC–MS method is currently regarded as a standard thiosulfate measurement, it requires complicated sample preparation prior to analysis. This study presents a simple, rapid, and highly sensitive method for the quantitative analysis of thiosulfate using liquid chromatography–tandem mass spectrometry (LC–MS/MS).