Abstract

Luncheon Seminar

Day 3: Friday, May 20 12:10-13:10 Room B (Seiun 1)

Introduction of Agilent AssayMAP for accelerating the development of Biotherapeutics

(Agilent)
Masahiko Kinoshita, oTakeshi Serino, Tomoyuki Hosono, Hiroyuki Fukuda

Monoclonal antibodies are a rapidly growing class of biotherapeutics whose rigorous characterization by mass spectrometry requires reproducible denaturation and digestion. Agilent AssayMAP Peptide Sample Prep Solution is an automated solution for protein digestion, peptide cleanup, and fractionation. It is based on the powerful combination of miniaturized, packed bed chromatography (Affinity, reversed-phase, cation exchange, IMAC etc.), the state-of-the-art Bravo Liquid Handling Platform, and a simple, applications-based user interface that creates an open access environment for both novices and experienced users and simplifies the most challenging sample preparation workflows. This streamlined solution dramatically reduces hands on time while improving reproducibility and throughput.