1B-O1-1645 PDF
Time- and Temperature-Resolved Proton Transfer Reactions of Peptide Ions
Time- and temperature-resolved proton transfer reactions of peptide ions, [M + zH]z+, to primary and secondary amines, diamines, and pyridine groups were examined in the gas phase. Absolute reaction rate constants for proton transfer were determined from intensities of parent and product ions in the mass spectra. With changes of reaction time and reaction temperature, remarkable change was observed for distribution of product ions and reaction rate constants. The results indicate that there exist plural conformations on [M + 2H]2+ at lower temperature range. It relates to conformation changes of [M + 2H]2+ with change of temperature, which are induced by complex formation. An issue that is attracting considerable attention is their conformations might resemble structural evolution that originated from temperature in the gas phase.