1B-O1-1640 PDF
Conformations of Protein Ions Probed by Proton Transfer Reactions at Various Temperature
Proton transfer from multiply-protonated protein ions to gaseous molecules was studied in the gas phase. Absolute reaction rate constants for proton transfer were determined from intensities of parent and product ions in the mass spectra. Temperature dependence of reaction rate constants and branching fractions for proton transfer was measured. An issue that is attracting considerable attention is vacuo conformations might resemble structural evolution that originated from temperature in the gas phase.