オーラルセッション
- 第1日 5月11日（月） 16:30～16:50 A会場（特別会議場)
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1A-O1-1630 PDF
プロテオミクス解析から明らかになるユビキチン修飾のバイオロジー
Ubiquitination is a versatile post-translational modification essential for nearly all aspects of cellular functions. Proteomics analysis has become an indispensable tool to elucidate the complexity of ubiquitin modifications. In this presentation, we will introduce PRM-based quantification strategies to characterize cellular functions of ubiquitin chains, substrates identification by TMT/MS2 analysis with ion mobility separation, and middle-down MS to analyze complexity of ubiquitin modifications.