Oral Sessions (Day1, Day2, Day3)
Poster Presentations
(Day1, Day2, Day3)
Plenary Lectures
- Day 2, May 16(Thu.) 14:50-15:40 Room A (Main Hall)
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2A-PL-1450 PDF
Charge Detection Mass Spectrometry: Instrumentation and Applications
Charge detection mass spectrometry (CDMS) provides a way to measure accurate masses for highly heterogeneous samples into the gigadalton regime. CDMS is a single particle technique where the mass of each ion is determined from simultaneous measurement of its mass to charge ratio (m/z) and charge. CDMS opens the door to the analysis of high mass, heterogeneous samples such as as vaccines and gene therapy products. Recent developments in instrumentation that have improved the accuracy and speed of CDMS measurements will be described along with several recent examples of applications to the analysis of bio-pharmaceuticals, virus assembly and disassembly, and antibody binding.