日本質量分析学会 第67回質量分析総合討論会

演題概要

オーラルセッション

第3日 5月17日(金) 10:30~10:50 E会場(201)

結晶スポンジレーザー脱離イオン化質量分析による微量構造解析法の開発

(徳島文理大院薬)
o林侑加子小原一朗山口健太郎

We have developed crystalline sponge laser desorption ionization mass spectrometry (CS-LDI MS) to elucidate molecular structure based on two different analytical approaches, X-ray and MS analysis. Although we observed the ions of encapsulated π-conjugated ene compounds, 11- and 15-membered ring compounds in the CS were not ionized. Single crystal X-ray analysis showed that the presence and absence of the interaction between CS framework and analyte. It indicated that the efficiency of ionization for analyte is critically depended on whether the interaction between CS framework and analyte is present or not. Another feature of CS is structure determination of unknown compounds. The reason is that the elemental composition can often be known from MS. In general, it is difficult to identify atomic species with similar numbers of electrons by X-ray analysis.