日本質量分析学会 第67回質量分析総合討論会

演題概要

オーラルセッション

第3日 5月17日(金) 09:30~09:50 E会場(201)

歯周病診断法開発に向けた唾液中の代謝物マーカーの探索

(1阪大院理2阪大歯病3阪大院歯)
o奥山萌恵1大須賀潤一1青木順1野﨑剛徳2村上伸也2,3豊田岐聡1

Periodontal disease is one of the most concerned threats to oral health. In addition, correlation with systemic diseases such as diabetes, rheumatoid arthritis and cardiovascular disease have also been reported recently. Therefore, it is important to establish a new method for diagnosing periodontal disease in an early stage. Additionally, it was suggested that periodontitis progression could be observed with a changing metabolite profile. In this study, saliva samples of healthy volunteers and mild to moderate periodontitis patients were analyzed by gas chromatography/mass spectrometry (GC/MS). As a result, some metabolites in saliva were found to be significantly different between healthy volunteers and patients.