日本質量分析学会 第66回質量分析総合討論会

Program

Poster Presentations

Day 4, May 18(Fri.)  Poster

Proteomics Profiling of Diabetic Mellitus Patient Urine for Discovery Biomarkers

(1Niigata Univ. BBC, 2Niigata Hosp., 3Shinrakuen Hosp.)
oYoshitoshi Hirao1, Suguru Saito1, Hidehiko Fujinaka2, Shigeru Miyazaki3, Xu Bo1, Quadery Ali1, Elguoshy Amr1, Keiko Yamamoto1, Tadashi Yamamoto1

Diabetic mellitus is a disease that affect glucose homeostasis and causes complications, such as diabetic nephropathy. For early diagnosis of DN, microalbuminuria is currently one of the most frequently used for biomarker. However, more early diagnostic biomarkers are desired in addition to microalbuminuria. In this study, we performed comprehensive proteomics analysis of urine proteomes of DM patient without microalbuminuria and healthy volunteers to compare the protein profiles by mass spectrometry.