Oral Sessions
（Day1, Day2, Day3, Day4）
Poster Presentations
（Day1, Day2, Day3, Day4）
Luncheon Seminars
（Day1, Day2, Day3, Day4）
Plenary Lectures
- Day 4, May 18（Fri.） 13:15-14:15 Room A (OrBit Hall)
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4A-PL-1315 PDF
Mass Spectrometric Technologies and their Application to Signaling and Clinical Proteomics
Mass spectrometry-based proteomics is now being employed in a wide variety of applications spanning the entire breadth of molecular biology1. However, the technology is no were near its technological limits and great instrumental advances continue to be made. Here, I will discuss a few of these, including the BoxCar method to fill the Orbitrap mass spectrometer more efficiently and gaining about an order of magnitude in dynamic range. Another interesting direction is the combination of ion mobility with time of flight mass spectrometry, in particular in the format of trapped ion mobility or TIMS. This technology can be used for parallel storage and serial fragmentation of peptides (PASEF technology), which enables very fast sequencing without loss of sensitivity.