日本質量分析学会 第66回質量分析総合討論会

Program

Poster Presentations

Day 1, May 15(Tue.)  Poster

Visualization of Sampling and Ionization Processes in Scanning Probe Electrospray Ionization Mass Spectrometry (SPESI-MS)

(1Osaka Univ., 2Shizuoka Univ.)
oBui Kamihoriuchi1, Yoichi Otsuka1, Aya Takeuchi1, Futoshi Iwata2, Takuya Matsumoto1

Tapping-mode scanning probe electrospray ionization (t-SPESI) realizes the mass imaging using a capillary probe. Although the formation of a liquid bridge and an electrospray enables the ambient sampling ionization (ASI), the dynamic behavior of the charged liquid at the probe apex is unclear. In order to study the process of ASI with t-SPESI, we have developed the optical detection method of a probe motion. The time dissolved measurements indicated the formation/breakage of a liquid bridge and the subsequent ionization of sampled molecules. We also analyzed the the mechanical property of the probe by finite element calculation.