Program

Poster Presentations

Day 1, May 15（Tue.）　　Poster

1P-30　　PDF

Steric Structures and Proton Transfer Reactions of Insulin and Insulin Chain B Ions

(Yokohama City Univ.)
^oYu Usui, Hayato Sasaoka, Hoshiyuri Oji, Shinji Nonose

Peptide or protein involved in biomolecules function different types from the structure of the original materials. The purpose of this research is to study the three-dimensional structures of the biomolecular ions in reactions with gaseous molecules. We studied proton transfer reactions of insulin (Ins) ions and insulin chain B (Ins B) ions in the gas phase. We used a tandem mass spectrometer with electrospray ionization (ESI). We changed temperature, retention time in the collision cell, and DC voltage of octapole ion guide (DC-OPIG) of the cell. The target molecules used were 1, 4-butanediamine (Bda). By changing DC-OPIG, remarkable change was observed for reaction rate constants and distribution of product ions.