Program

Oral Sessions

Day 1, May 15（Tue.）　14:25-14:45　Room A (OrBit Hall)

1A-O1-M-1425　　PDF

Development of next generation metabolome analytical technologies for trans-omics

(Kyushu Univ.)
^oTakeshi Bamba

Many researchers have been working on the development of various metabolomics technologies for more than 10 years. So far, various metabolomics methods have been constructed by using analytical platforms such as NMR, GC/MS, CE/MS, LC/MS, and SFC/MS. However, there remains room for improvement in the coverage of metabolites, quantitative performance, reproducibility, differences between experimental errors in different batches, etc. Additionally, it is necessary to develop a dynamic analysis system, because most metabolomics methods provide snapshots and cannot provide information about dynamic changes. Therefore, further improvements in analytical and data-mining techniques are needed to develop a more general and global approach to metabolomics.
Our group is working on developing technologies of metabolome analysis that could contribute to trans-omics research. In particular, we have been actively involved in the progress in various technological developments such as production of stable isotope-labeled standards and labeling probes for quantitative analysis, quantitative wide-targeted metabolome analytical systems, and individual quantitative analytical systems for each metabolite group to acquire quantitative metabolome information.