演題概要

ポスター発表

第1日 5月17日(水)  P会場(多目的ホール)

新規の四重極スキャンによるDIAメソッドと迅速なマイクロボアカラムによる代謝物プロファイリング(RAMMP)を組み合わせたメタボロミクスワークフロー

(1ウォーターズ2日本ウォーターズ)
Gethings, Lee1Hughes, Chris1Keith, Richardson1Jason, Wildgoose1Johannes, Vissers1Langridge, James1oパクストンタナイ2

Introduction

Previous studies utilizing rapid microbore metabolic profiling (RAMMP) have shown comparable group discrimination and improved selectivity over conventional UPLC chromatography. Here we demonstrate improvements of the workflow by coupling RAMMP with a novel DIA method (SONAR) to provide qualitative and quantitative information for metabolomic based applications.

Novel Aspect

Implementation of RAMMP with a novel DIA (SONAR) workflow results in higher and more confident numbers of metabolite identifications at increased sample throughput.