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第1日 5月17日(水)  P会場(多目的ホール)

FAB条件下における誘導体化単糖の[M - H]+イオンの生成機構

(1武庫女大薬2小野薬品工業3横市大4聖マリアンナ医大)
o堀山志朱代1市川厚1藤田節子2高山光男3中山登4

Fast atom bombardment ionization is known as one of a soft ionization method for mass spectrometry, because using matrix like glycerol. Usually, we get the protonated molecule [M+H]+, but on occasion, positive molecular ions M+ and dehydride molecules [M-H]+ are formed under positive ion FAB conditions. The processes of formation of [M-H]+ had been studied and some report proposed the structure could form the [M-H]+1,2). The [M-H]+ was appeared at positive ion FAB mass spectra of certain derivatized monosaccharide. We clarified the 1-methoxy-4-methoxymethyl benzene moiety is play an important role in formation of [M-H]+ .