演題概要

オーラルセッション

第1日 5月17日(水) 15:45~16:05 B会場(102)

臨床検査室導入に向けた質量分析の役割と問題点:ビタミンD測定を中心に

(千葉大病院)
o佐藤守野村文夫

Mass spectrometry (MS) is a powerful analytical tool used in an increasing number of clinical laboratories around the world. Sensitivity, stability at low concentration range, and linearity are excellent as compared to those of immunoassays because the analyte can be measured directly by MS without using antibody. However, clinical use of this technique has still been limited to large institutions and reference laboratories and has not yet been widely used in hospital laboratories in Japan. There are several reasons for this; sample preparation and measurements are not automated, and IVD reagents are not commercially available. We are working on application of LC-MS/MS to clinical laboratory on a routine basis. I would like to present and discuss our research efforts, focusing on vitamin D analysis in this session.