演題概要

ポスター発表

第２日　５月１５日（木）　　会場（月光）

2P-18　　PDF

LC/MS用Desalination in Real Time“DESIRT”技術の開発

(¹エムエス・ソリューションズ・ ²東農大)
^o高橋豊¹・ 芥川一成²・ 小川桂一²・ 清水和美²・ 工藤昭英²・ 千葉一裕²

Non-volatile buffers in RPLC are useful to obtain good separation of complex mixtures, it is well known, however, that the non-volatile buffers cannot be used for LC/MS. The following problems cause by using non-volatile buffers.
1. Co-existing non-volatile salts suppress the ionization of analytes.
2. Non-volatile salts cause the clogging the capillary and the serious contaminations.
Even if what "non-volatile buffer cannot use fundamentally" becomes the common sense of LC/MS, in addition in LC/MS, use of non-volatile buffer is desired. So we have developed the desalination interface that could continuously remove the non-volatile salts from mobile phase by using the micro-fluidic technology and magnetic TiO2 particles.