2P-12 PDF
薬毒物分析における超高速LC-MS/MSの有用性
In Forensic Toxicology, LC/MS/MS has become a preferred method for the routine quantitative and qualitative analysis of drugs of abuse. LC/MS/MS allows for the simultaneous analysis of multiple compounds in a single run, thus enabling a fast and high throughput analysis. In this study, we report a developed analytical system using ultra-high speed triple quadrupole mass spectrometry with a new extraction method for pretreatment in forensic analysis. The system has a sample preparation utilizing modified QuEChERS extraction combined with a short chromatography column that results in a rapid run time making it suitable for routine use.